Vitamin D 1000 IU/day each month increases blood levels 8-10 nmol/L ?

Discussion in 'General Discussion' started by Jason, May 31, 2017.

  1. Jason

    Jason Developer / Handyman Staff Member

    I read this
    Successful treatment of reactive airways dysfunction syndrome by high-dose vitamin D

    At this stage, the immunological properties of vitamin D were being reported, and we began a trial of high-dose oral vitamin D 2000 IU/day. Vitamin D levels were requested, but her local hospital did not routinely perform this test. As a result, measurement at our hospital was arranged at her next visit. This showed a vitamin D level of 57 nmol/L at eight weeks after commencing the high dose. Scientific data from osteoporosis research shows a rise of 8–10 nmol each month on a vitamin D dose of 1000 IU/day. This would suggest that our patient’s vitamin D level was <25 nmol/L, initially consistent with severe deficiency. History-taking confirmed no ingestion of oily fish and no sunlight exposure or sunbathing for many years. At the start of vitamin D therapy, her symptoms were severe with incessant cough and bronchial hyper-reactivity as described before, which made measurement of formal lung function difficult. Her chest remained clear on physical examination, and she had a C-reactive protein of 0.2 and an immunoglobulin E of 9 kU/L.​

    High-dose vitamin D has been continued and blood levels have remained at 150–200 nmol/L with normal calcium levels. There are no reported adverse effects of regular vitamin D at doses of up to 5000 IU/day. The current recommendation for adults is now 1000 IU/day. There were no side effects of the vitamin D, but oral preparations are known to have a mild laxative effect and increase skin oils that may cause spots.​

    Q: What do you think of that statement ?
  2. Graham

    Graham Developer Staff Member

    I think it's funny ... that 2000 IU/day is considered high.
    But there's other research to link airways reactivity to both D3 levels and also vegetable intake. The latter may act on gut biome which is also implicated in airways inflammation

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