Herpes vaccine ? HSV-1 / HSV-2 - seems like a good idea to me ...

Jason · Mar 19, 2014

Another day, another Zovirax prescription !

Zovirax Ointment apply qid prn M:30g

One of two herpes simplex viruses—HSV-1 or HSV-2—causes genital herpes. It used to be believed that HSV-1 caused herpes infections of the mouth (often thought of as cold sores) and HSV-2 was responsible for those infections of the genitals, but researchers now understand that either virus can infect the genitals or the mouth. Still, the vaccines in development are focused on HSV-2, as it remains the cause of most genital infections.
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Interesting.

http://rhrealitycheck.org/article/2013/11/12/progress-seen-in-efforts-to-create-herpes-vaccine/

NIH launches trial of investigational genital herpes vaccine Embargoed for Release: Friday, November 8, 2013, 9 a.m. EST

Researchers have launched an early-stage clinical trial of an investigational vaccine designed to prevent genital herpes disease. The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, is sponsoring the Phase I trial, which is being conducted at the NIH Clinical Center in Bethesda, Md.

Genital herpes is one of the most common sexually transmitted infections in the United States. Most genital herpes cases are caused by infection with herpes simplex virus type 2 (HSV-2); however, herpes simplex virus type 1 (HSV-1) can also cause genital herpes. An estimated 776,000 people in the United States are infected with HSV-2 or HSV-1 each year. There is no vaccine to prevent genital herpes.

“Although genital herpes is treatable, it is a lifelong infection that can exact a substantial psychological and physical toll on infected individuals and places them at higher risk of acquiring HIV,” said NIAID Director Anthony S. Fauci, M.D. “Furthermore, mothers with active genital herpes infection at time of delivery can transmit the virus to their newborns, which can lead to severe illness and death.”

“A protective vaccine would help to reduce significantly the spread of this all-too- common sexually transmitted infection,” Fauci added.

Led by principal investigator Lesia K. Dropulic, M.D., of NIAID’s Laboratory of Infectious Diseases, the trial will test an investigational HSV-2 vaccine candidate, called HSV529, for safety and the ability to generate an immune system response. The investigational vaccine manufactured by Sanofi Pasteur was developed by David Knipe, Ph.D., professor of microbiology and immunobiology at Harvard Medical School, Boston.

Preclinical testing of the candidate vaccine involved a 10-year collaborative effort between Dr. Knipe and Jeffrey Cohen, M.D., chief of NIAID’s Laboratory of Infectious Diseases. The experimental product is a replication-defective vaccine, meaning that scientists have removed two key proteins from the vaccine virus so that it cannot multiply to cause genital herpes.
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That's good.

source: http://www.nih.gov/news/health/nov2013/niaid-08.htm

Jason · Mar 19, 2014

60-90% adults are seropositive for HSV.
20-40% get outbreaks (usually cold sores on mouth, lips).

That's alotta HSV !

Graham · Mar 20, 2014

Eat lots of broccoli !

Jason · Mar 21, 2014

Graham said: ↑

Eat lots of broccoli !
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For the immunity ?

Graham · Mar 21, 2014

http://www.webmd.com/genital-herpes/news/20030915/broccoli-may-thwart-herpes-virus

Jason · Mar 21, 2014

Maybe in a test tube
Probably should stick to condoms for now.

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Herpes vaccine ? HSV-1 / HSV-2 - seems like a good idea to me ...

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Herpes vaccine ? HSV-1 / HSV-2 - seems like a good idea to me ...

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